Performance data

Fast-acting—significant reductions in target lesions seen as early as 4 hours*¹

Clinically proven low-dose 2.5% benzoyl peroxide delivers consistent full-face treatment and helps prevent stubborn acne without overdrying or stinging.

Superior aesthetics and high tolerability promote daily use for results that last

• Vanishes instantly into the skin and dries clear
• Allows for application under a daily moisturizer or cosmetics
• Fragrance-free; no burning/stinging or excessive dryness in the vast majority of patients¹

The dynamic duo—your patients’ new AM/PM regimen

• For best results, use them together—Neutrogena Stubborn Acne™ AM Treatment and Neutrogena Stubborn Marks™ PM Treatment
• The retinol SA (sustained action) patented ingredient in Neutrogena Stubborn Marks™ PM Treatment improves the look of post-acne marks
• Learn more about the effective AM/PM Treatment regimen

Gentle on the skin¹

Highly tolerated by over 90% of patients in the 8-week clinical trial.*
• *Data shown are from a study of 34 patients aged 12 to 30 years with mild to moderate acne. The study assessed efficacy and tolerability over 8 weeks of twice-daily treatment.
• At the 8-week time point, over 90% of patients experienced either improvement or no change in erythema, dryness, peeling, and burning/stinging when compared to baseline scores.
2. Data on file, Johnson & Johnson Consumer Inc.

Drug Facts

Use

For the treatment of acne.

Warnings

For external use only.
Allergy alert Get medical help right away if you develop hives, swelling of eyes and mouth, blistering, or difficulty breathing.
Do not use
•  on sensitive skin
• if you are allergic to benzoyl peroxide. 
Ask a doctor or pharmacist before use if you
• have severe acne 
• are pregnant or breastfeeding.
When using this product
• skin irritation and dryness are more likely to occur when using another topical acne product at the same time. If irritation occurs, use only one product at a time
• avoid contact with eyes, lips, mouth, and nostrils. If contact occurs, rinse thoroughly with water
• avoid contact with hair and dyed fabrics, which may be bleached by this product 
• avoid unnecessary sun exposure and use a sunscreen.
Stop use and ask a doctor if
• you develop severe irritation, burning or itching of the skin
• improvement is not apparent within 6-8 weeks.
Keep out of reach of children. If swallowed, call a poison control centre or get medical help right away.

Directions

Adults and children 12 years and older:
• Cleanse skin thoroughly before applying product
For New Users:
• Apply product to a small area once a day for three days to test if you are sensitive to this product
• If no discomfort occurs, cover the entire affected area with a thin layer 
• Start with one application daily, then gradually increase to two or three times daily, if needed 
• If dryness or peeling occurs, reduce application to once a day or every other day. 

Inactive ingredients

Carbomer Homopolymer type B, Chlorphenesin, Disodium EDTA Ethylhexylglycerin, Hydroxypropyl Methylcellulose, Laureth-4, Sodium Hydroxide, Water (eau).